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The BIOFIRE System and Your Immune System

The BIOFIRE System provides syndromic infectious disease testing, empowering healthcare providers to select the most appropriate test the first time. Patients benefit from faster diagnosis and more targeted treatments. Clinicians benefit from improved stewardship for antibiotics. Labs improve efficiency and cost savings.

The BioFire FilmArray Pneumonia plus panel (PN panel) examines native sputum, endotracheal aspirate, and bronchoalveolar lavage specimens (including mini-BAL) for 33 clinically relevant pathogens and antimicrobial resistance genes, with semiquantitative results within an hour.

Respiratory

The burning of biomass, including plants, wood and other organic materials, creates gaseous pollution and fine particulates that negatively affect the respiratory system. Climate change can make it more difficult to reverse the negative effects of forest bioethanol fuel fires to human health.

In the United States wildfire smoke is linked to hospitalizations due to respiratory diseases such as asthma, Biofuel fireplace insert COPD, and lung cancer. Additionally, this kind of air pollution can be an important risk factor for cardiovascular diseases and a significant contributing factor to the burden of disease for the most vulnerable population which includes those with lower socioeconomic status (SES).

Wildfires have led to unhealthy levels of air pollution in several communities during the COVID-19 epidemic. However, the public health response to this environmental issue is sporadic and mainly focused on communication about symptom management. This knowledge gap is alarming due to the fact that smoking cigarettes and other causes of air pollution can lead to health problems.

Researchers are now evaluating the best ways to protect public's health during future events of this nature. NIH is funding research into this important public health issue through the BLUE CORAL study and its successor FIRE CORAL.

First time an prospective study will examine the long-term effects of exposure to smoke from wildfires and other sources. FIRE CORAL is seeking adult participants hospitalized for the index episode of COVID-19 who are fluent in English or Spanish and are not pregnant. The FIRE CORAL protocol includes a series of in-person assessments objectively measuring the pulmonary function test and lung imaging, as well as functional assessment.

Smoke and other particles can cause or worsen chronic respiratory conditions such as emphysema, COPD and pneumonia. There are a variety of steps that can be taken to stop or lessen the negative health effects of exposure to smoke, which includes avoidance of outdoor activities whenever possible and using the EPA's "N95" mask, which is designed to capture fine particles.

Smoke can also cause irritation to the throat and eyes and can cause an irritated nose. To minimize symptoms, the lungs should be flushed by drinking plenty of water and taking medicines that reduce inflammation, like corticosteroids.

Bloodstream

The bloodstream is your first line of defense against germs that invade your system. Dendritic cells are specialized cells that are like your indoor bio ethanol fire fire (http://it-viking.ch/index.php/ethanol_for_fire_tools_to_streamline_your_daily_lifethe_one_ethanol_For_fire_trick_every_person_should_Be_able_to) department's call center; they gather antigens (molecules that trigger an immune response) from invaders and release proteins to trigger other white blood cells to come fight them. The total white blood cells, differentials, and band cells increased following firefighters' firefighting tasks in comparison to levels after vigorous exercise that did not include firefighting.

Skin

Dermatologists were concerned that smoke and ash of the California wildfires could have negative effects on the skin of those exposed to these substances. Maria Wei is a graduate student at the University of California, Irvine. She studies how extreme wildfire pollution impacts the skin. Her research was published in Scientific Reports on April 22.

The research of Wei shows that the temperature of the skin changes depending on how long the body is exposed to flames. It takes upwards of two hours for a person's skin to reach its flash point -- the place where it begins to burn and turns into a ashy. That's why it's important to not stay near the campfire or a fire, and why you should wear protective clothing if you are outdoors during a forest fire or even the heat of the day.

Forest fires will continue occur, despite the steps taken to stop the spread of wildfires. Wei is predicting that the number of people suffering the effects of wildfires will grow as climate change causes more forests to burn. This means that more people will need to wear long sleeves, hats and thick moisturizers.

It's also worth noting that the atopic dermatitis (itchy skin) which many suffer from is often exacerbated by wildfire air pollution. She says that the particles in smoke can clog up pores and cause atopic skin to become worse.

Another issue is that atopic dermatitis is known to make people more sensitive to UV light, which can be aggravated by smoke from wildfires. This can result in people seeking out tanning salons and apply a tan with less protection.

A treatment with ice and fire can help reduce atopic skin dermatitis symptoms however it is not recommended for those with an open wound or rash. Patients who have active acne should avoid it If you're nursing or pregnant, it is recommended to stay clear of this procedure altogether. The IS Clinical Fire & Ice Facial at Novuskin, Las Vegas' most prestigious membership MedSpa It's a highly effective, results-driven facial that bridges the gap between a gentle facial and a peel, without requiring any downtime. It's designed to smooth skin, improve rosacea and reduce the appearance of acne scars and fine lines and also stimulate cellular renewal. This is a fantastic treatment to give your skin a radiant glow.

Infections

The human body is a complex network of organs and tissues that work to guard us against infection. Infections can be caused by microorganisms like parasites, viruses and bacteria that infect healthy cells and cause them to multiply uncontrollably. If this occurs your immune system could react with symptoms of illness. These symptoms can be anything from a snoring nose to a stomach that is upset, but can also include a fever, swollen lymph glands, or an skin rash. The type of infection and its location can affect your symptoms.

Infections can be spread through a variety of methods, but the most common are spread from person to through droplets that linger in the air after coughing or sneezing. This is how bacterial infections like strep, tuberculosis and meningococcal illness, as well as viral infections like the common cold and influenza are spread. Certain bacterial infections, such as skin infections or sexually transmitted diseases (STIs) such as gonorrhea or chlamydia are spread by direct contact with infected mucous surfaces or tissues, or indirectly through contaminated surfaces. Certain bacterial infections are transmitted by bugs like ticks, mosquitoes or fleas, and are transmitted when they bite you.

Viruses, parasites and other microorganisms are tiny enough to be able to get into your bloodstream to infect your cells. This can lead to serious illnesses such as the common cold or AIDS. Fungi can cause skin conditions such as ringworm and athlete's foot and others can infect the respiratory tract and nervous system.

The BioFire Panel employs our revolutionary FilmArray technology to analyze the bronchoalveolar and sputum samples to determine a comprehensive list of pathogens that are involved in upper respiratory infection. The kit comes with a reagent bag that includes all the chemistry required to perform reverse transcription as well as nested multiplex PCR detection in a single machine. It's a simple solution to help clinicians syndromicly identify and treat patients suffering from various respiratory symptoms. This test has been granted an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high-complexity labs.